Assay
Age
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In situ reporter (knock in)
10.5 DPC
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Hand1 heart and neural crest derivatives expressed 1 (Synonyms: bHLHa27, eHAND, Ehand1, Hxt, Th1, Thing1) | |
Results | Reference |
1* | J:165398 Barnes RM, Firulli BA, Conway SJ, Vincentz JW, Firulli AB, Analysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivatives. Dev Dyn. 2010 Nov;239(11):3086-97 |
1 | J:94514 McFadden DG, Barbosa AC, Richardson JA, Schneider MD, Srivastava D, Olson EN, The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development. 2005 Jan;132(1):189-201 |
1 | J:89474 Morikawa Y, Cserjesi P, Extra-embryonic vasculature development is regulated by the transcription factor HAND1. Development. 2004 May;131(9):2195-204 |
1 | J:138404 Vincentz JW, Barnes RM, Rodgers R, Firulli BA, Conway SJ, Firulli AB, An absence of Twist1 results in aberrant cardiac neural crest morphogenesis. Dev Biol. 2008 Aug 1;320(1):131-9 |
1* | J:294964 Vincentz JW, Firulli BA, Toolan KP, Arking DE, Sotoodehnia N, Wan J, Chen PS, de Gier-de Vries C, Christoffels VM, Rubart-von der Lohe M, Firulli AB, Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function. Circ Res. 2019 Aug 30;125(6):575-589 |
1 | J:181316 Vincentz JW, VanDusen NJ, Fleming AB, Rubart M, Firulli BA, Howard MJ, Firulli AB, A Phox2- and Hand2-dependent Hand1 cis-regulatory element reveals a unique gene dosage requirement for Hand2 during sympathetic neurogenesis. J Neurosci. 2012 Feb 8;32(6):2110-20 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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